Pharmacological Exploration of Rumex vesicarius: A Review

Introduction: Sorrel, also known as Bladder dock or Rumex vesicarius, is native to the Mediterranean and Eurasia but is cultivated in many other regions, including India and the Middle East. It is renowned for its diverse range of therapeutic benefits. Methods: The narrative review was based on a literature search using Scopus, PubMed, Dimension AI, Google Scholar, and Google database. Results: Studies have demonstrated that it possesses properties that promote wound healing, act as an antidiabetic agent, fight against fungal infections (antifungal), eliminate parasitic worms (antihelmintic), eradicate bacteria (antibacterial), relieve diarrhea (antidiarrheal), and provide protection against oxidative stress (antioxidant). In addition, it provides nephroprotective, hepatoprotective, neuroprotective, and cardioprotective effects and has demonstrated anticancer qualities along with the capacity to relax tracheal muscles. The pharmacological properties of this herb are significantly improved when extracted with methanol, suggesting that the methanolic extract is particularly strong. It is particularly plentiful in a range of flavonoids, such as 8-C-glucosyl-apigenin and catechin, among others. The effectiveness of the plant extract is found to increase in a manner that is dependent on the dosage, indicating that greater doses result in more notable therapeutic effects. The therapeutic potential of Rumex vesicarius has been confirmed through biomarker evaluation, validating its beneficial properties. Discussion: The review discussed the potential beneficial pharmacological effects of Rumex vesicarius. Conclusion: This review offers significant insights into the ongoing research performed to discover and investigate these features. The results highlight the potential of Rumex vesicarius as a valuable medicinal plant