PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
April 14, 2026CureusOpen Access

Effect of Short-Term Vitamin D3 Supplementation on Blood Pressure in Patients With Hypertension: A Pilot Study From a Tertiary Care Hospital

View Full Paper
Ask AI
Bookmark
Share

Authors

SJSanthoshakumari T M JMJMathivanan JRKRamachandran K

Discussion

Loading...

Member takes

Overview

Pilot study investigates vitamin D3's effect on blood pressure in hypertension patients, suggesting limited clinical significance.

Key Points

  • The study evaluates the effects of short-term vitamin D3 supplementation on blood pressure among patients with essential hypertension.
  • Prospective interventional pilot study design
  • Inclusion of 30 adult patients with essential hypertension
  • Vitamin D3 supplementation at 250 IU daily for 12 weeks
  • Monitoring of blood pressure and serum 25-hydroxyvitamin D levels at baseline and after 12 weeks
  • Statistical analysis using Wilcoxon signed-rank test for paired comparisons.
  • Systolic blood pressure decreased from 133 mmHg to 132 mmHg after 12 weeks (p < 0.001)
  • Diastolic blood pressure decreased from 94 mmHg to 92 mmHg after 12 weeks (p < 0.001)
  • Serum 25-hydroxyvitamin D levels increased from 27 ng/mL to 28 ng/mL after supplementation (p < 0.001)
  • 12 participants had normal vitamin D levels, 11 had insufficiency, and 7 had deficiency at baseline
  • Reductions in blood pressure were statistically significant but small.

Cite This Study

J et al. (2026) studied this question.

synapsesocial.com/papers/69ddd9f9e195c95cdefd774ahttps://doi.org/10.7759/cureus.106876
View Full Paper
Ask AI
Bookmark
Share