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April 15, 2026Open Access

Concurrent Patent Foramen Ovale and Pulmonary Arteriovenous Malformation Etiology

Key Points

To investigate the relationship between patent foramen ovale and pulmonary arteriovenous malformations as congenital abnormalities.
Review of medical literature on PFO and PAVM
Analysis of incidence rates
Assessment of clinical implications related to shunting
Identified PFO and PAVM as co-occurring conditions
Documented increased risk of paradoxical embolism in individuals with both
Highlighted need for further research on their etiology

Abstract

Patent foramen ovale (PFO) and pulmonary arteriovenous malformations (PAVMs) are congenital vascular abnormalities that can lead to right-to-left shunting, potentially causing paradoxical embolism.

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Authors

A

A Al Qaraghuli

K

Kalyan R. Chitturi

B

Beni Rai Verma

Journals

JACC Case Reports

Actions

Institutions

National Institutes of Health

National Heart Lung and Blood Institute

MedStar Washington Hospital Center

References and Citations

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Cite this study

Qaraghuli et al. (Wed,) studied this question.

www.synapsesocial.com/papers/69df2a99e4eeef8a2a6afaa2 — DOI: https://doi.org/10.1016/j.jaccas.2026.107746

Concurrent Patent Foramen Ovale and Pulmonary Arteriovenous Malformation Etiology | Synapse