Imaging Characteristics of Pancreatic Neoplasms: A Case Series with Radiologic-pathologic Correlation

Background: Pancreatic neoplasms encompass a heterogeneous group of benign and malignant lesions with overlapping clinical presentations but distinct imaging characteristics. Early and accurate diagnosis is essential for appropriate management and prognostication. Objective: To evaluate CT and MRI features of various pancreatic neoplasms and correlate them with clinical and histopathological findings. Methods: A retrospective case series (2024–2025) at a tertiary care center. Imaging findings from CT, MRI, and PET-CT were analyzed along with clinical, surgical, and histopathological data. Results: Five representative cases—adenocarcinoma, insulinoma, solid pseudopapillary epithelial neoplasm (SPEN), mucinous cystic neoplasm, and serous cystadenoma—demonstrated characteristic imaging patterns aiding diagnosis. Conclusion: Cross-sectional imaging plays a crucial role in characterization, diagnosis, and management planning of pancreatic neoplasms.