What question did this study set out to answer?

This research focuses on understanding the implications of misfolded proteins in eye conditions, particularly vitreous amyloidosis.

April 15, 2026Open Access

Misfolded Proteins in the Eye – Vitreous Amyloidosis

Key Points

This research focuses on understanding the implications of misfolded proteins in eye conditions, particularly vitreous amyloidosis.
Assessment of vitreous opacities
Implementation of diagnostic vitrectomy
Evaluation of systemic diseases such as ATTRv amyloidosis
Exploration of non-invasive imaging techniques for diagnosis
Identification of atypical presentations of vitreous opacities
Confirmation that diagnostic vitrectomy is effective for diagnosing underlying diseases
Potential for novel imaging techniques to assist in the diagnosis of vitreous amyloidosis

Abstract

While vitreous opacities are a common usually benign phenomenon, it is important to recognise atypical presentation. Diagnostic work-up may include diagnostic vitrectomy, which can aid in diagnosing relevant underlying systemic disease such as ATTRv amyloidosis. While pathologic work-up of vitreous material is the current gold standard, there may be novel non-invasive imaging techniques to aid in diagnosis of vitreous amyloidosis.

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Discussion

Authors

Katrin Fasler

Eléonore Multone

Marc Stahel

Journals

Retinal Cases & Brief Reports

Actions

Institutions

University Hospital of Zurich

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Misfolded Proteins in the Eye – Vitreous Amyloidosis

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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