Pulmonary Function Deficit and Clinical Associations in Childhood Acute Lymphoblastic Leukaemia Survivors: A National Retrospective ALL‐STAR Lungs Cohort Study

Key Points

• The study aims to assess pulmonary function deficits in childhood acute lymphoblastic leukaemia (ALL) survivors and their clinical associations.
• Conducted a national retrospective cohort analysis of childhood ALL survivors.
• Examined pulmonary function specifically after stem cell transplantation and pulmonary disease.
• Analyzed small airway function and diffusing capacity for better monitoring.
• Pulmonary function deficits were frequently observed in childhood ALL survivors.
• Deficits were particularly notable in those who underwent stem cell transplantation.
• Tailored monitoring strategies are recommended for early detection and intervention.

Abstract