Evaluation of consistency in adverse event reporting between trial registry and publications in COVID-19 pharmacological intervention trials

Key Points

• This research evaluates the consistency of adverse event reporting between trial registries and published results in COVID-19 pharmacological trials.
• Analyzed adverse event reporting from trial registries
• Compared data with published outcomes
• Focused on pharmacological interventions for COVID-19
• High discrepancy rate observed between trial registry reports and published results
• Inconsistencies could impact patient safety and treatment guidelines
• Findings indicate a need for improved transparency in clinical trial reporting

Abstract