Skin-deep connections: likelihood of skin-scarring history in patients with stricturing/penetrating Crohn disease compared with patients with nonstricturing/nonpenetrating disease and non–inflammatory bowel disease controls

Key Points

• This study aims to explore the connection between skin scarring and different forms of Crohn disease.
• Conducted a cross-sectional proof-of-concept analysis.
• Compared patients with stricturing/penetrating Crohn disease to those with nonstricturing disease and non-IBD controls.
• Assessed the frequency of hypertrophic and keloid scars.
• Patients with stricturing/penetrating Crohn disease exhibited significantly more hypertrophic and keloid scars.
• Potential shared mechanisms of fibrosis were suggested between skin and intestinal conditions.
• Findings indicate a need for further research in larger, longitudinal studies.

Abstract