Adherence-enhancing intervention and relapse in childhood acute lymphoblastic leukemia: results from the Children’s Oncology Group randomized trial ACCL1033

Key Points

• The study aims to assess the effectiveness of an adherence-enhancing intervention on relapse rates in children with acute lymphoblastic leukemia.
• Participants included children under 12 years old diagnosed with acute lymphoblastic leukemia.
• Two groups were assigned: one receiving adherence education and another focusing on interventional methods.
• Follow-up duration averaged 7.7 years per participant.
• The adherence-enhancing intervention led to differences in relapse rates between groups.
• Comparative analysis between EDU and IP groups indicates notable outcomes that may influence treatment practices.

Abstract