The chemoselective oxidation of sulfides to sulfoxides is accomplished using a new family of photocatalysts, namely 1,2,6‐thiadiazin‐4‐ones. Utilizing a low catalyst loading (0.01 mol%), a 440 nm lamp as the irradiation source, and molecular oxygen as the oxidant, this rapid method is applicable to a broad range of alkyl‐aryl, dialkyl, and diaryl sulfides. Additionally, the method demonstrates practical relevance for the industrially significant synthesis of pharmaceutical compounds, including modafinil and sulforaphane.
Karaousta et al. (2026) studied this question.