Copper and manganese diazacalix4arene complexes: structural and cytotoxicity studies and use in ring opening polymerization of ε-caprolactone and δ-valerolactone

Key Points

• The study aims to investigate the structural properties and cytotoxic effects of copper and manganese diazacalix[4]arene complexes.
• Synthesis of metal complexes from M(OAc)2•nH2O (M=Cu, Mn) and p-MeLH4 under aerobic conditions
• Characterization of complexes through structural analysis
• Assessment of cytotoxicity in vitro
• Evaluation of polymerization activity with ε-caprolactone and δ-valerolactone
• Isolated azacalixarene-metal complexes are thermally stable and non-toxic at low concentrations
• Successful polymerization of ε-caprolactone and δ-valerolactone observed
• Complexes demonstrate significant potential for use in materials science applications

Abstract