A case of breathlessness and unexpected antibodies: stating the obvious

Key Points

• To investigate the relationship between pravastatin use and the onset of breathlessness and antibodies in a patient.
• Case report of a patient with breathlessness after starting pravastatin.
• Assessment of antibodies and interstitial changes was conducted.
• Statin withdrawal was performed as an intervention to evaluate recovery.
• The patient showed transient positivity for anti-HMGCR antibodies.
• Breathlessness improved fully after stopping pravastatin.
• Findings underscore the need for careful drug causality assessment in interstitial lung disease.

Abstract