Interaction of bi-nuclear gallium(III) complexes with human serum albumin and impact on potency towards osteosarcoma stem cells

Puntos clave

• The study aims to investigate how bi-nuclear gallium(III) complexes interact with human serum albumin and affect osteosarcoma stem cells.
• Analyzed the binding of gallium complexes to human serum albumin.
• Examined the effects on osteosarcoma stem cells' growth and differentiation.
• Used biochemical assays to determine potency levels of gallium complexes against stem cell populations.
• Gallium complexes show significant binding affinity for human serum albumin.
• The presence of these complexes reduces the viability of osteosarcoma stem cells.
• Potency against resistant stem cell populations increases with gallium complex concentration.