Pilot study reveals diverse musculoskeletal involvement patterns in hidradenitis suppurativa, suggesting effective treatments.
Key Points
This pilot study aims to characterize musculoskeletal involvement patterns in patients with hidradenitis suppurativa and evaluate the impact of treatment.
Retrospective observational pilot study on patients with hidradenitis suppurativa and concurrent musculoskeletal symptoms.
Data collected on disease severity, joint involvement patterns, presence of enthesitis, and treatment outcomes.
Patients stratified into axial, peripheral, and mixed musculoskeletal phenotypes.
Laboratory markers like glycated hemoglobin evaluated for metabolic associations.
62.5% of patients presented with peripheral arthritis, 12.5% with axial involvement, and 25% with mixed phenotypes.
75% of patients showed enthesitis, primarily affecting the Achilles tendon and plantar fascia.
Metabolic dysfunction observed in 62.5% of patients with obesity and 75% had fatty liver disease and elevated HbA1c levels.
Biologic therapies, particularly IL-17 inhibitors, were more effective for symptom control compared to NSAIDs and TNF inhibitors.