Synthesis, molecular modeling and anti-inflammatory activity of new benzoapyrano2,3-cphenazine compounds

Puntos clave

• The aim is to develop new benzo[a]pyrano[2,3-c]phenazine compounds and evaluate their anti-inflammatory effects.
• Developed a microwave-assisted three-component synthetic approach
• Utilized benzo[a]phenazin-5-ol, benzaldehyde derivatives, and enaminone derivatives
• Synthesized sixteen new derivatives
• Successfully synthesized sixteen new benzo[a]pyrano[2,3-c]phenazine derivatives
• Demonstrated potential anti-inflammatory activity of the synthesized compounds