Does IV thrombolysis with tenecteplase improve functional outcomes at 90 days in patients >80 years with minor stroke and visible occlusion or perfusion lesion?
patients >80 years with minor stroke and visible occlusion or perfusion lesion
IV thrombolysis with tenecteplase
nonthrombolytic standard of care therapies
functional outcomes at 90 dayshard clinical
In patients over 80 years old with minor ischemic stroke, IV tenecteplase is associated with worse functional outcomes at 90 days compared to standard of care.
This study provides Class III evidence that in patients >80 years with minor stroke and visible occlusion or perfusion lesion, IV thrombolysis with tenecteplase is associated with worse functional outcomes at 90 days compared with nonthrombolytic standard of care therapies.
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Aravind Ganesh
Shabnam Vatanpour
Amy Ying Xin Yu
Neurology
University of British Columbia
University of Alberta
University of Glasgow
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Ganesh et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69e1cd6f5cdc762e9d856fd2 — DOI: https://doi.org/10.1212/wnl.0000000000214925