A low C-reactive protein–albumin–lymphocyte (CALLY) index was an independent predictor of all-cause mortality after TAVI (HR 3.80; 95% CI 2.03–7.11; p < 0.001).
Cohort (n=303)
No
Does the baseline CALLY index predict all-cause mortality in patients undergoing TAVI for severe aortic stenosis?
A low baseline CALLY index is a strong, independent predictor of all-cause mortality in patients undergoing TAVI, offering a potential complementary biomarker for risk stratification.
Estimación del efecto: HR 3.80 (95% CI 2.03-7.11)
valor p: p=<0.001
Background and Objectives: This study investigated the prognostic value of the C-reactive protein–albumin–lymphocyte (CALLY) index in predicting all-cause mortality among patients undergoing transcatheter aortic valve implantation (TAVI) for severe aortic stenosis. Materials and methods: This retrospective single-center study included 303 patients who underwent TAVI. The CALLY index and other established prognostic scores were calculated at baseline. Patients were followed for a median of 21 months. The primary endpoint was all-cause mortality. Results: A total of 60 patients (19.8%) died during follow-up. The CALLY index demonstrated the highest predictive performance for all-cause mortality, with an AUC of 0.698 (95% CI: 0.628–0.768, p < 0.001). In multivariate Cox regression, a low CALLY index remained an independent predictor of mortality (HR: 3.80, 95% CI: 2.03–7.11, p < 0.001), along with reduced LVEF, chronic kidney disease, and diabetes mellitus. Kaplan–Meier analysis further confirmed markedly worse survival in the high-risk group (log-rank p < 0.001). Conclusions: The CALLY index was independently associated with mortality after TAVI and may represent a complementary biomarker for risk stratification in this population.
Güner et al. (Wed,) conducted a cohort in severe aortic stenosis (n=303). CALLY index vs. High CALLY index was evaluated on all-cause mortality (HR 3.80, 95% CI 2.03-7.11, p=<0.001). A low C-reactive protein–albumin–lymphocyte (CALLY) index was an independent predictor of all-cause mortality after TAVI (HR 3.80; 95% CI 2.03–7.11; p < 0.001).