What question did this study set out to answer?

To explore the occurrence of licorice-induced pseudoaldosteronism in an infant treated with rikkunshito.

April 17, 2026Open Access

Licorice‐Induced Pseudoaldosteronism Caused by Rikkunshito in an Extremely Low Birth Weight Infant

Key Points

To explore the occurrence of licorice-induced pseudoaldosteronism in an infant treated with rikkunshito.
Case report of an extremely low birth weight infant
Monitored symptoms like hypokalemia and metabolic alkalosis
Treatment involved rikkunshito and potassium supplementation
Infant experienced persistent hypokalemia and metabolic alkalosis after rikkunshito treatment
Symptoms resolved after discontinuing rikkunshito and providing potassium supplementation

Abstract

We report an extremely low birth weight infant with gastroesophageal reflux disease who developed persistent hypokalemia and metabolic alkalosis after treatment with rikkunshito. These findings gradually resolved after discontinuation of rikkunshito and potassium supplementation, suggesting licorice-induced pseudoaldosteronism.

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Discussion

Authors

Toshihiro Nakayama

Naofumi Hanyu

Shonosuke Nara

Journals

Pediatrics International

Actions

Institutions

Tokyo Medical University

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Licorice‐Induced Pseudoaldosteronism Caused by Rikkunshito in an Extremely Low Birth Weight Infant

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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