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April 18, 2026CureusOpen Access

Acquired Hemophilia A (AHA) Associated With Malignancy and Antiphospholipid Antibodies: Two Case Reports With Distinct Etiologies

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Authors

NHN. HtunHWHsan Theingi WinMAMohammad A Abdullah

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Overview

Case reports showcase distinct causes of AHA in older men, indicating management complexities.

Key Points

  • The aim is to present two cases of acquired hemophilia A with differing underlying causes.
  • Two case reports of patients diagnosed with acquired hemophilia A.
  • Laboratory evaluations confirmed the presence of factor VIII inhibitors.
  • Patients received various treatments including corticosteroids and factor replacement therapies.
  • Both cases achieved clinical and laboratory improvement following targeted treatments.
  • One patient had malignancy-associated AHA, while the other had AHA linked to antiphospholipid antibodies.
  • Early recognition of symptoms led to timely diagnosis and intervention.

Cite This Study

Htun et al. (2026) studied this question.

synapsesocial.com/papers/69e31f1a40886becb653e858https://doi.org/10.7759/cureus.107103
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