The aim is to understand how contextual factors and genetic risk contribute to dementia and cognitive decline in older adults.
Analyzed data from the Multi-Ethnic Study of Atherosclerosis
Adjusted for age, sex, education, and genetic risk
Examined the impact of contextual determinants on dementia and cognition
Contextual determinants show a significant association with dementia
Late-life cognition is also influenced by these determinants after adjustments
Polygenic risk factors contribute to understanding dementia risk.
Resumen
Contextual determinants are associated with dementia and late-life cognition after adjusting for age, sex, education, and genetic risk.
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Integrating contextual determinants and polygenic risk to examine dementia and late‐life cognition in the Multi‐Ethnic Study of Atherosclerosis | Synapse