PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 18, 2026Journal of Cardiothoracic Surgery0 citationsOpen Access

Multiple lung metastases from typical type A thymoma after long-term follow-up: a case report

KTKeita TobariTTTsuyoshi TakahashiASAtsushi Sano

Key Result

A 74-year-old man developed multiple lung metastases from a typical type A thymoma 9 years after initial detection, remaining stable without adjuvant therapy for 2 years post-resection.

Key Points

  • To present a case of multiple lung metastases from a typical type A thymoma and discuss long-term monitoring.
  • Case presentation of a 74-year-old man with a history of anterior mediastinal nodule.
  • Simultaneous thymectomy and wedge resection performed.
  • Histopathological examination confirmed diagnosis and presence of metastases.
  • Multiple lung metastases were identified 9 years after initial nodule detection.
  • No progression or new lesions observed during 2-year follow-up.
  • Secondary malignancy of prostate cancer was diagnosed postoperatively.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
74-year-old man with typical type A thymoma and multiple lung metastases, identified 9 years after initial detection of an anterior mediastinal nodule, and concurrent prostate cancer.
I
Intervention
Simultaneous thymectomy and wedge resection of the pulmonary nodule

This case highlights the potential for distant metastasis in patients with otherwise indolent, typical type A thymomas, emphasizing the need for long-term surveillance of at least 10 years.

Limitations

  • The timeline of pulmonary metastasis development from thymoma during the 9 years remains unclear.
  • The exact mechanisms of secondary carcinogenesis related to thymoma remain unconfirmed due to the limited number of reported cases.

Abstract

Abstract Background Typical type A thymomas are slow-growing tumors generally associated with a favorable clinical course, and distant metastasis is exceedingly rare. Case presentation We report a case of multiple lung metastases from a typical type A thymoma in a 74-year-old man, identified 9 years after the initial detection of an anterior mediastinal nodule. The patient underwent simultaneous thymectomy and wedge resection of the pulmonary nodule. Histopathological examination confirmed a diagnosis of typical type A thymoma with pulmonary metastases. Postoperatively, the patient was also diagnosed with prostate cancer as a secondary malignancy. At 2-year follow-up, without any postoperative treatment, there was no evidence of progression or development of new pulmonary lesions. Conclusion This case underscores the potential for distant metastasis in patients with otherwise indolent, typical type A thymomas, highlighting the need for long-term surveillance.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Tobari et al. (2026) conducted a case report in Typical type A thymoma with multiple lung metastases (n=1). Simultaneous thymectomy and wedge resection was evaluated. A 74-year-old man developed multiple lung metastases from a typical type A thymoma 9 years after initial detection, remaining stable without adjuvant therapy for 2 years post-resection.

synapsesocial.com/papers/69e3211640886becb65403abhttps://doi.org/10.1186/s13019-026-04045-5
Ask AI
Helpful
Bookmark
Share
View Full Paper