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April 18, 2026The Analyst0 citations

Nanopore-based enzyme-assisted biomarker detection method for chronic obstructive pulmonary disease

QRQianyuan RenYYYakun YiSLShihong Li

Key Points

  • This research aims to develop a sensitive detection method for biomarkers related to COPD and pulmonary hypertension.
  • Developed a nanopore-based detection system
  • Utilized enzyme-assisted reactions for enhanced sensitivity
  • Conducted tests comparing the new method with existing diagnostics
  • Analyzed diagnostic performance using clinical samples
  • The new method shows significantly improved detection sensitivity compared to traditional methods
  • It successfully identified biomarkers associated with COPD and PH at early stages
  • Demonstrated potential for clinical application in diagnosing complex respiratory conditions

Abstract

Chronic obstructive pulmonary disease (COPD) is frequently complicated by pulmonary hypertension (PH), yet early diagnosis remains challenging due to overlapping clinical features and limited detection sensitivity. Herein, we present a...

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Cite This Study

Ren et al. (2026) studied this question.

synapsesocial.com/papers/69e3213840886becb6540679https://doi.org/10.1039/d6an00373g
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