Organoid Models through the Lens of Metabolomics: A Systematic Review of Experimental Applications and Analytical Approaches

Key Points

• The aim is to explore the use and analytical methods of organoid models in experimental biology with a focus on metabolomics.
• Systematic review of existing literature on organoid models and metabolomics
• Analysis of experimental applications in various biological contexts
• Evaluation of analytical techniques utilized in metabolomics
• Organoid models offer superior recapitulation of tissue structures compared to traditional cultures
• Metabolomics provides insights into metabolic pathways active within organoid systems
• Diverse applications in cancer research, drug development, and regenerative medicine have been identified