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April 18, 2026Journal of the International AIDS Society0 citationsOpen Access

Impact of Tenofovir Alafenamide Sub‐Dermal Implant Insertion Site Scarring on Acceptability and HIV Prevention Preferences: A Prospective Cohort Study in Durban, South Africa

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TGTanuja N. GengiahLLLara LewisIHIshana Harkoo

Key Points

  • The study aims to assess the effect of scarring from tenofovir alafenamide implant insertion on its acceptability and preferences for HIV prevention among women.
  • Prospective cohort study design
  • Participants previously enrolled in a TAF implant trial
  • Assessment of scarring post-implant removal
  • Evaluation of preferences for PrEP options
  • Mild but persistent scarring noted after implant removal
  • Limited cases of hyperpigmentation and induration observed
  • 12-monthly implant remained the most preferred PrEP option among women

Abstract

Mild but persistent scarring was observed following TAF implant removal, with limited cases of hyperpigmentation and induration. Despite these local side effects, a 12-monthly implant remained the most preferred PrEP option among women previously enrolled in the TAF implant trial.

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Cite This Study

Gengiah et al. (2026) studied this question.

synapsesocial.com/papers/69e3216540886becb6540b43https://doi.org/10.1002/jia2.70107
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