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April 19, 2026Arab Journal of Urology0 citationsOpen Access

Dorsal onlay buccal mucosal graft urethroplasty for female urethral stricture disease: A single-center retrospective study

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UQUvaisullah QuadirSPSajad Ahmad ParaARAamir Bashir Raina

Key Points

  • This research examines the effectiveness of dorsal onlay buccal mucosal graft urethroplasty in treating female urethral stricture disease.
  • Retrospective review of 53 women undergoing surgery from January 2019 to July 2024.
  • Analysis of demographics, symptom profiles, operative details, and postoperative outcomes.
  • Comparison of uroflowmetry, postvoid residual, and IPSS scores before and after surgery.
  • Mean age of participants was 47.6 years, with 73.6% being premenopausal.
  • Significant improvements were noted with increased Qmax and decreased PVR and IPSS (all p < 0.0001).
  • Continence maintained in 94% of cases, with 7.5% experiencing recurrence, mainly managed with a single dilatation.
  • Overall complications were recorded at 18.9%, primarily minor.

Abstract

Introduction Female urethral stricture disease (FUSD) is an uncommon but often overlooked cause of lower urinary tract symptoms in women. Many undergo repeated dilatations or urethrotomies with limited durability, leading to progressive fibrosis and delayed definitive care. Dorsal onlay buccal mucosal graft urethroplasty (BMGU) has emerged as a reliable reconstructive option. This study evaluates functional outcomes and complications following dorsal BMGU in women with FUSD.Methods A retrospective review was performed of 53 women who underwent dorsal onlay BMGU between January 2019 and July 2024 at a tertiary care center. Demographics, symptom profile, investigations, operative details, postoperative outcomes, complications and recurrence were analyzed. Uroflowmetry, postvoid residual (PVR) and International Prostate Symptom Score (IPSS) were compared before and after surgery. Mean follow-up was 30 months.Results Mean age was 47.6 ± 11.3 years, with 73.6% premenopausal. Voiding symptoms were most common and 45.3% had undergone prior dilatation or urethrotomy. Mean stricture length was 2.8 ± 0.7 cm. All procedures were completed successfully. Qmax increased while PVR and IPSS dropped significantly (all p < 0.0001). Continence was preserved in 94%. Recurrence occurred in 7.5%, mostly managed with a single dilatation. Overall complications were 18.9%, predominantly minor.Discussion/Conclusion Dorsal onlay BMGU provides significant improvement in flow, bladder emptying and symptoms, with low recurrence and minimal effect on continence. Results are valuable. This study strengthens existing evidence and highlights the importance of timely reconstruction in affected women for care.

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Cite This Study

Quadir et al. (2026) studied this question.

synapsesocial.com/papers/69e470a4010ef96374d8d8c8https://doi.org/10.1080/20905998.2026.2657144
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