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April 19, 2026Infectious Diseases and Therapy0 citationsOpen Access

Epidemiology of Acute Cystitis or Afebrile Urinary Tract Infection in Adult Men: A Systematic Literature Review

MGMary E. GeorgiouPWPriscilla WittkopfAMAmber L. Martin

Key Points

  • This review aims to summarize existing research on acute cystitis and afebrile urinary tract infections in adult men while identifying gaps in the literature.
  • Conducted a systematic literature review
  • Analyzed variations in study design and inclusion criteria
  • Reviewed definitions of acute cystitis and afebrile UTIs
  • Identified a low number of relevant studies
  • Highlighted the variability in study definitions and criteria
  • Recommended conducting larger population-based studies to address antimicrobial resistance and recurrence rates in men.

Abstract

The low number of studies identified, coupled with variations in study design, inclusion criteria, and uUTI definitions, negated effectively describing acute cystitis epidemiology in men. There is a need for large, population-based studies, leveraging standard definitions for acute cystitis/afebrile UTI and focusing on AMR burden and recurrence rates to positively inform and improve clinical care in men with uUTI.

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Cite This Study

Georgiou et al. (2026) studied this question.

synapsesocial.com/papers/69e470a4010ef96374d8d952https://doi.org/10.1007/s40121-026-01346-z
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