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April 19, 2026ACS OmegaOpen Access

Ratiometric Fluorescent Test Strips Based on Lysozyme-Stabilized Carbon Dots and Gold Nanoclusters Encapsulated in ZIF-8 for High-Selective Detection of Copper Ions

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Authors

JYJia YuMFMiao FanHXHongbo Xu

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Overview

Demonstrates a ratiometric fluorescent sensor for copper ion detection, highlighting its high selectivity and sensitivity.

Key Points

  • To develop a highly sensitive ratiometric fluorescent sensor for the selective detection of Cu2+ ions using encapsulated nanoparticles.
  • Coupling of gold nanoclusters and carbon dots with lysozyme
  • Encapsulation of the coupled nanoparticles in ZIF-8
  • Preparation of CD@SiO2@AuNC@ZIF-8 for sensor application
  • Testing for fluorescence response to varying Cu2+ concentrations
  • The sensor exhibited a linear response to Cu2+ concentrations between 0.04–4 μM
  • Achieved a limit of detection of 33 nM for Cu2+
  • Fluorescence intensity of gold nanoclusters quenched while carbon dots remained stable
  • Integrated smartphone photo technology for visual detection applications

Cite This Study

Yu et al. (2026) studied this question.

synapsesocial.com/papers/69e470e9010ef96374d8d9e5https://doi.org/10.1021/acsomega.6c00715
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