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April 19, 2026Current Oncology0 citationsOpen Access

Protective Effects of Plant-Based Diets Against Colorectal Cancer

Protective Effects of Plant-Based Diets Against Colorectal Carcinogenesis via Modulation of Key Cellular and Molecular Mechanisms: A Comprehensive Review of Evidence

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Authors

MKMarina KamelCWClarence WongEGEduardo Grunvald

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Overview

Comprehensive review demonstrates plant-based diets reduce colorectal cancer risk, suggesting a promising prevention strategy.

Key Points

  • This review aims to summarize the protective role of plant-based diets against colorectal carcinogenesis and the underlying mechanisms.
  • Reviewed existing literature on plant-based dietary patterns and colorectal cancer.
  • Analyzed effects on gut microbiota, immunity, and metabolic processes.
  • Investigated cellular and molecular mechanisms involved in cancer prevention.
  • Plant-based diets enhance gut microbial health and immune regulation.
  • These diets promote production of short-chain fatty acids and apoptosis in cancer cells.
  • Plant-derived foods reduce inflammation and oxidative stress, downregulating tumorigenesis-related pathways.

Cite This Study

Kamel et al. (2026) studied this question.

synapsesocial.com/papers/69e4734c010ef96374d8f13bhttps://doi.org/10.3390/curroncol33040222
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