A woman in her 70s presented with low-grade fevers and painful subcutaneous nodules on both thighs 1 year ago.A skin biopsy revealed an inflammatory cell infiltrate with fibrin thrombi in small arteries.A tentative diagnosis of polyarteritis nodosa was made.Contrast-enhanced computed tomography (CT) showed no vascular inflammation.She was treated with diaphenylsulfone, after which the rash resolved and C-reactive protein (CRP) fell from 16.5 to 0.5 mg/dL.
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Tomoaki Saito
Saeko Yamada
Remi Kawashima
University of Tokyo Hospital
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Saito et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69e7138bcb99343efc98cfcc — DOI: https://doi.org/10.1016/j.ero.2026.03.015