A report of 2 identical twins requiring aortic valve replacement for stenosed bicuspid aortic valves supports a potential genetic influence in the development of the condition.
Case Report
A pair of identical twins (probably monozygotic) with aortic stenosis occurring in bicuspid aortic valves (n=2)
Aortic valve replacement
The presence of bicuspid aortic valve with stenosis in identical twins supports a genetic component to the condition.
Hereditary factors may have a part to play in the development of bicuspid aortic valve. This report concerns a pair of identical twins, probably monozygotic, who required aortic valve replacement as a result of aortic stenosis occurring in bicuspid aortic valves. This supports the contention that there may be a genetic influence in the development of bicuspid aortic valve, though environmental factors may be of greater importance.
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David Godden
Preetinder Sandhu
F. Kerr
European Heart Journal
University of Aberdeen
Raigmore Hospital
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Godden et al. (Sun,) conducted a case report in Bicuspid aortic valve with aortic stenosis (n=2). Aortic valve replacement was evaluated. A report of 2 identical twins requiring aortic valve replacement for stenosed bicuspid aortic valves supports a potential genetic influence in the development of the condition.
www.synapsesocial.com/papers/69e795668a4862ceef5c8dcd — DOI: https://doi.org/10.1093/oxfordjournals.eurheartj.a062276