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April 22, 2026Experimental Lung Research0 citationsOpen Access

The downregulation of RAB10 by miR-574-5p alleviates the inflammatory response in neonatal respiratory distress syndrome

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YJYanan JiYZYangping ZhouLDLudan Deng

Key Points

  • To investigate the role of the miR-574-5p/RAB10 signaling axis in neonatal respiratory distress syndrome (NRDS) and its potential as a therapeutic target.
  • Examined the miR-574-5p/RAB10 signaling interaction.
  • Analyzed inflammation responses in cellular models of NRDS.
  • miR-574-5p downregulates RAB10, reducing inflammation in NRDS.
  • Identified potential molecular markers for early diagnosis of NRDS.

Abstract

This study demonstrated that the miR-574-5p/RAB10 signaling axis plays a crucial role in regulating the inflammation in NRDS. This not only provides potential molecular markers for the early diagnosis of NRDS but also identifies miR-574-5p as a potential therapeutic target for NRDS.

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Cite This Study

Ji et al. (2026) studied this question.

synapsesocial.com/papers/69e864c46e0dea528dde9705https://doi.org/10.1080/01902148.2026.2645470
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