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April 23, 2026JACC Case Reports0 citationsOpen Access

Cardioneuroablation Restoring Atrioventricular Conduction in Brugada Syndrome

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FCFredy ChipaJBJosep BrugadaALAgustin Leonardo Lujan

Key Result

Cardioneuroablation restores atrioventricular conduction in Brugada syndrome, offering a durable alternative to pacemakers for young patients with functional AV block.

Key Points

  • To evaluate the effectiveness of cardioneuroablation in restoring atrioventricular conduction in patients with Brugada syndrome.
  • Assessing vagally mediated functional bradyarrhythmias through atropine testing.
  • Performing cardioneuroablation as an intervention for atrioventricular block.
  • CNA provided a physiological approach to restore atrioventricular conduction.
  • Patients showed a significant response to atropine testing, indicating improved cardiac function.

Structured PICO

Does cardioneuroablation restore atrioventricular conduction in young patients with Brugada Syndrome and functional atrioventricular block?

P
Population
Young patients with Brugada Syndrome (BrS) and functional atrioventricular block
I
Intervention
Cardioneuroablation (CNA)
O
Outcome
Restoration of atrioventricular conduction

Cardioneuroablation may serve as a physiological and durable alternative to pacemaker implantation for young patients with Brugada Syndrome and functional AV block.

Abstract

In BrS, vagally mediated functional bradyarrhythmias may respond to atropine testing. CNA offers a physiological and durable alternative to pacemaker implantation in young patients with functional atrioventricular block.

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Cite This Study

Chipa et al. (2026) studied this question. Cardioneuroablation restores atrioventricular conduction in Brugada syndrome, offering a durable alternative to pacemakers for young patients with functional AV block.

synapsesocial.com/papers/69e9b62685696592c86eade5https://doi.org/10.1016/j.jaccas.2026.107843
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Catheter Ablation for Brugada Syndrome2019 · 7 citations
  2. 2Ablation for the treatment of Brugada syndrome: current status and future prospects2020 · 13 citations
  3. 3Catheter Ablation for Brugada Syndrome2021 · 1 citations
  4. 4Epicardial multisite conduction blocks detected by equispaced electrode array and omnipolar technology in Brugada syndrome2022 · 4 citations
  5. 5Recent advances in the treatment of Brugada syndrome2018 · 19 citations