PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 23, 2026Journal of Cardiothoracic Surgery0 citationsOpen Access

Effect of preoperative respiratory prehabilitation on cardiopulmonary function in patients undergoing lung resection for non-small cell lung cancer: a randomized controlled trial

FHFeiyan HuangPKPengxu KongJLJingjing Liu

Key Points

  • This research aims to evaluate the impact of preoperative respiratory prehabilitation on cardiopulmonary function in patients undergoing lung resection for cancer.
  • Conducted a randomized controlled trial with patients undergoing lung resection.

Structured PICO

Does a 7-day preoperative respiratory prehabilitation program improve postoperative pulmonary function in patients undergoing lung resection for non-small cell lung cancer?

P
Population
120 patients with suspected non-small cell lung cancer (NSCLC) scheduled to undergo curative-intent thoracoscopic anatomical lobectomy or wedge resection, age 18-75 years, ECOG performance status 0-1, tumor diameter ≤ 2.0 cm, and preserved pulmonary function (FEV1 > 1.5 L or FEV1% ≥ 60%).
I
Intervention
7-day preoperative respiratory prehabilitation program (including training device use, abdominal breathing, upper limb exercise, and lower limb exercise) plus routine perioperative care.
C
Comparator
Routine perioperative care alone (no structured, supervised, or quantified preoperative respiratory training program).
O
Outcome
Pulmonary function on postoperative day 7, assessed by forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and peak expiratory flow (PEF).surrogate

A 7-day preoperative respiratory prehabilitation program significantly improves early postoperative pulmonary function and cardiopulmonary exercise capacity in patients undergoing lung resection for non-small cell lung cancer.

Limitations

  • Exploratory design
  • Relatively small sample size
  • Short-term nature of assessed outcomes
  • No formal sample size calculation based on a prespecified primary endpoint
  • No formal multiplicity adjustment
  • Serial preoperative spirometry performed only in the intervention group

Abstract

Medical Research Registration and Record Information System of the National Healthcare Security Information Platform, MR-33-25-019022.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Huang et al. (2026) studied this question.

synapsesocial.com/papers/69e9b6aa85696592c86eb134https://doi.org/10.1186/s13019-026-04142-5
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Role of Pulmonary Rehabilitation Programs in Patients with Lung Cancer: A Narrative Review2026 · 1 citations
  2. 2Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial2022 · 1,740 citations
  3. 3Systematic short-term pulmonary rehabilitation before lung cancer lobectomy: a randomized trial2017 · 133 citations
  4. 4[Application Research of Narrative Care to the Management of Symptom Clusters and Post-traumatic Growth in Patients Undergoing Lung Cancer Surgery].2025 · 3 citations
  5. 5Preoperative pulmonary rehabilitation before lung cancer resection: Results from two randomized studies2011 · 282 citations