Human Papillomavirus (HPV) is the leading cause of sexually transmitted infections worldwide. Male HPV infection contributes towards disease burden in males and plays a crucial role in transmission to females. This is especially significant in Lower Middle-Income Countries (LMICs) which bear 90% of the global cervical cancer burden. Most existing data on male HPV prevalence come from high-income countries, yet evidence from LMICs is crucial for informing cost-effective male HPV vaccination and targeted prevention strategies. Present study was conducted to estimate the prevalence of penile HPV infection and to identify factors associated with HPV infection among 20–70-year-old men in Sri Lanka. A community-based cross-sectional study was conducted using multi-stage probability-proportionate cluster sampling to recruit 579 participants. Consented study participants were referred to the identified clinic for data and penile swab collection. HPV was detected using PCR with GP5+/GP6 + primers, and positives were confirmed by Sanger sequencing. Chi-square test was used with a significance level of p 1 female partner/s in their lifetime (p = 0.02; AOR: 2.4, 95%CI:1.1–4.9) and pre-marital sexual relationships (p = 0.04; AOR:3.5, 95%CI:1.04–12.1). High-risk sexual behaviours are contributed with HPV infection among males in Sri Lanka. Promoting safe sex practices, along with detection and monitoring of vaccine-preventable HPV genotypes among males, are vital for decision-making for HPV preventive strategies.
Amarasena et al. (Tue,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: