PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 23, 2026Chemical Communications0 citationsOpen Access

Mechanochemically-synthesised AIE-active receptors for selective ceftazidime sensing in high-water-content matrices

KMKrzysztof MelcerTDTim DavidBSBernd M. Schmidt

Key Points

  • Investigate a novel method for sensing ceftazidime using AIE-active receptors in water-rich environments.
  • Utilized mechanochemical synthesis to create water-insoluble, AIE-active dendritic receptors.
  • Performed selectivity tests against related β-lactams through titrations.
  • Employed DFT (Density Functional Theory) for computational analysis of interactions.
  • Achieved selective fluorescence detection of ceftazidime in up to 99 vol% water.
  • Confirmed selectivity over structurally related β-lactams via experimental titrations.
  • Demonstrated that AIE-active receptors perform effectively in high-water matrices.

Abstract

Mechanochemical synthesis of water-insoluble, AIE-active dendritic receptors enable selective fluorescence detection of ceftazidime in up to 99 vol% water. Selectivity over structurally related β-lactams was confirmed by titrations, DFT, and...

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Melcer et al. (2026) studied this question.

synapsesocial.com/papers/69e9ba6b85696592c86ec90fhttps://doi.org/10.1039/d6cc01502f
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rapid and Selective Cefuroxime Sensing via Gold Nanoparticle-Enhanced MIP-based Electrochemical Sensors2026 · 1 citations
  2. 2Sensing of ceftazidime antibiotics in human plasma through waveguide-enhanced Raman spectroscopy assisted by a mesoporous layer2025 · 2 citations
  3. 3Electrochemical Sensor Based on Molecularly Imprinted Polymer for Cefuroxime Detection in Biological and Environmental Samples2026
  4. 4A highly selective and swift-response AIE-active Schiff base chemosensor for ultra-sensitive detection of Fe( iii ) and picric acid: applications in real-world water/drug samples and bioimaging2025 · 2 citations
  5. 5Programmable Electrochemical Cefapirin Antibiotic Aptasensor Powered by Highly Conductive Bimetallic NiCu(HITP) MOF and Dendritic DNA Amplifications2026