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Synapse
April 23, 2026Open Access Government0 citations

Be involved in funding an exciting new technology for clinical medicine

BTBrian Tait

Key Points

  • To advocate for funding a new technology that improves the assignment of phase to multiple mutations in clinical settings.
  • Utilizing established alleles and sequencing to determine haplotypes like the HLA system.
  • Employing linkage disequilibrium for defining alleles.
  • Applying next-generation and third-generation sequencing to assess both chromosomes individually.
  • Achieves theoretical accuracy of 100% in determining alleles.
  • Provides a novel method for haplotype determination in clinical applications.
  • Enhances the understanding of genetic variations in individuals.

Abstract

Be involved in funding an exciting new technology for clinical medicine Brian Tait, Chief Scientific Officer at Haplomic Technologies Pty Ltd, calls for public support to fund exciting groundbreaking technology for assigning phase to multiple mutations – a unique contribution to clinical medicine. New groundbreaking technology for assigning phase to multiple mutations – a unique contribution to clinical medicine. The method can be used in one of two ways. In cases where alleles have been well established and sequenced, it can be used to determine haplotypes such as the HLA system. In cases where alleles have been defined by linkage disequilibrium (LD) between single nucleotide polymorphisms (SNPs), by next-generation sequencing (NGS) or by third-generation sequencing, it can be used to determine both alleles present in an individual by the sequencing of both chromosomes separately, with theoretical 100% accuracy.

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Cite This Study

Brian Tait (2026) studied this question.

synapsesocial.com/papers/69e9baa885696592c86ecbe6https://doi.org/10.56367/oag-050-11937
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Single chromosome sequencing with Haplomic Technologies2025
  2. 2Long-range PCR and Nanopore sequencing for localisation and phasing variants: an end-to-end clinical application workflow2025
  3. 3Bone marrow transplantation and haplotyping2025
  4. 4High resolution <scp>HLA</scp> genotyping with third generation sequencing technology—A multicentre study2024 · 3 citations
  5. 5Abstract 6912: Phasing tumor clones by timing point mutations using bulk long-read sequencing.2026