What does this research mean for the field?

Myasthenia gravis care in Spain is transitioning toward ambulatory management, characterized by declining hospital admissions and increasing day-hospital and emergency department utilization, without worsening short-term hospital outcomes or in-hospital mortality. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This analysis aims to evaluate hospitalisation trends and outcomes related to myasthenia gravis in Spain from 2016 to 2022.

April 23, 2026Neurological Research and PracticeOpen Access

Trends in hospitalisation, myasthenic crisis and intensive care use in myasthenia gravis: a nationwide population-based study in Spain (2016–2022)

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Authors

TGTania Garrido‐Hernández JDJavier Del-Águila-Mejía MRMarta Rodríguez-Camacho

Discussion

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Overview

Population-based analysis reveals shifting hospital utilisation trends in myasthenia gravis, indicating safer outpatient care models.

Key Points

This analysis aims to evaluate hospitalisation trends and outcomes related to myasthenia gravis in Spain from 2016 to 2022.
Conducted a retrospective, population-based analysis using data from the Spanish Minimum Basic Data Set.
Evaluated hospital admissions, day-hospital visits, and emergency department encounters for myasthenia gravis.
Utilised segmented negative binomial regression models to analyse temporal trends and severity-related outcomes.
Hospital admissions declined by 5.4% annually after 2018, with increased day-hospital and ED utilisation.
ICU admissions rose from 8.2% to 13.7% of hospitalised patients, with myasthenic crisis accounting for 4.5% of admissions.
In-hospital mortality remained low and stable at a mean of 2.6%.

Cite This Study

Garrido‐Hernández et al. (2026) studied this question.

synapsesocial.com/papers/69e9bc1285696592c86ed4a5 https://doi.org/10.1186/s42466-026-00485-5

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April 23, 2026Neurological Research and PracticeOpen Access

Trends in hospitalisation, myasthenic crisis and intensive care use in myasthenia gravis: a nationwide population-based study in Spain (2016–2022)

View Full Paper

Ask AI

Bookmark

Authors

TGTania Garrido‐Hernández JDJavier Del-Águila-Mejía MRMarta Rodríguez-Camacho

Discussion

Member takes

Overview

Population-based analysis reveals shifting hospital utilisation trends in myasthenia gravis, indicating safer outpatient care models.

Key Points

This analysis aims to evaluate hospitalisation trends and outcomes related to myasthenia gravis in Spain from 2016 to 2022.
Conducted a retrospective, population-based analysis using data from the Spanish Minimum Basic Data Set.
Evaluated hospital admissions, day-hospital visits, and emergency department encounters for myasthenia gravis.
Utilised segmented negative binomial regression models to analyse temporal trends and severity-related outcomes.
Hospital admissions declined by 5.4% annually after 2018, with increased day-hospital and ED utilisation.
ICU admissions rose from 8.2% to 13.7% of hospitalised patients, with myasthenic crisis accounting for 4.5% of admissions.
In-hospital mortality remained low and stable at a mean of 2.6%.

Cite This Study

Garrido‐Hernández et al. (2026) studied this question.

synapsesocial.com/papers/69e9bc1285696592c86ed4a5 https://doi.org/10.1186/s42466-026-00485-5

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