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April 24, 2026International Journal of Surgery Case ReportsOpen Access

Hypotony following the use of topical carbonic anhydrase inhibitors in glaucoma patients: a case report and review of literature

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Authors

SASulaiman M. AlTariqiMHMohammed A. HalawaniNANayef D. AlOtaiby

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Overview

A case report highlights hypotony following carbonic anhydrase inhibitors in glaucoma patients, indicating a rare but significant risk.

Key Points

  • This research aims to explore the occurrence of hypotony associated with topical carbonic anhydrase inhibitors in glaucoma patients.
  • Case report of a 70-year-old patient with congenital glaucoma and hypotony after using dorzolamide.
  • Monitoring of intraocular pressure (IOP) after medication discontinuation.
  • Literature review on the effects and safety of carbonic anhydrase inhibitors.
  • The patient experienced marked hypotony, with IOP dropping to 4 mm Hg after starting dorzolamide.
  • Complete recovery of IOP to 18 mm Hg within 2 weeks after discontinuation of the medication.
  • Subsequent exposure to other CAIs led to similar hypotensive outcomes.

Cite This Study

AlTariqi et al. (2026) studied this question.

synapsesocial.com/papers/69eb092b553a5433e34b3b40https://doi.org/10.1097/rc9.0000000000000457
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