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April 24, 2026Organic Chemistry Frontiers0 citationsOpen Access

Ligand-controlled chemoselective nickel-catalyzed cross-electrophile coupling of cyclic anhydrides with alkyl bromides

TLTingzhi LinJJJunlong JiaYWYu Wu

Key Points

  • The research aims to develop a ligand-controlled nickel-catalyzed approach for chemoselective cross-electrophile coupling.
  • Utilized nickel as a catalyst for the coupling reaction.
  • Explored the role of ligands in controlling chemoselectivity.
  • Assessed the reaction between cyclic anhydrides and alkyl bromides.
  • Established a chemoselective method for C–C bond formation.
  • Demonstrated efficient coupling of cyclic anhydrides with various alkyl bromides.
  • Highlighted the influence of different ligands on reaction outcomes.

Abstract

The introduction of chemoselective transition-metal-catalyzed cross-electrophile coupling approaches continues to expand chemists’ pallet of C–C bond-forming reactions.

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Cite This Study

Lin et al. (2026) studied this question.

synapsesocial.com/papers/69eb0a94553a5433e34b49aehttps://doi.org/10.1039/d6qo00409a
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