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April 24, 2026Journal of Paediatrics and Child Health0 citations

Investigation for Bleeding Disorders in Suspected Non‐Accidental Intracranial Haemorrhage

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PSPetrisse E. SeeleyPMPaul MonagleLGLydia Garside

Key Points

  • To investigate the occurrence of bleeding disorders in cases of suspected non-accidental intracranial hemorrhage.
  • Conducted extensive haematological investigations including FBC and APTT
  • Identified inherited bleeding disorders in three patients
  • Proposed a screening protocol focusing on initial tests for bleeding risk
  • Three patients diagnosed with inherited bleeding disorders: haemophilia A, haemophilia B, and von Willebrand disease.
  • All three displayed abnormal APTT in initial testing.
  • Recommended a streamlined haematological screening approach.

Abstract

An extensive array of haematological investigations was performed, but with a lack of consistency. Three patients were identified to have an inherited bleeding disorder, including haemophilia A, haemophilia B and von Willebrand disease, two of whom were confirmed NAI regardless. All three had abnormal APTT on the initial coagulation screen. We propose initial haematological screening with FBC, PT/APTT/fibrinogen only, unless bleeding risk factors are identified. If an abnormality is detected, subsequent factor levels and further haematological investigations are recommended.

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Cite This Study

Seeley et al. (2026) studied this question.

synapsesocial.com/papers/69eb0ac4553a5433e34b4b0ahttps://doi.org/10.1111/jpc.70400
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