Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 24, 2026Nature CommunicationsOpen Access

Longitudinal protein profiling of blood during childhood into early adulthood

View Full Paper
Ask AI
Bookmark
Share

Authors

SBSofia BergströmSBSophia BjörkanderMÁMaría Bueno Álvez

Discussion

Loading...

Member takes

Overview

Longitudinal analysis identifies age- and sex-related protein changes in a population cohort, suggesting insights for health development.

Key Points

  • The aim is to analyze the changes in plasma proteins during youth into early adulthood and their implications for physiological development.
  • Longitudinally measured 5416 plasma proteins at four time points: ages 4, 8, 16, and 24.
  • Used Olink Explore HT technology for protein analysis in a population-based cohort.
  • Analyzed protein trajectories and sex-related differences across the age groups.
  • 54% of the studied proteins displayed age-related associations.
  • Identified protein trajectories relevant to bone, neural function, and hormonal control.
  • Notable sex-related differences were observed at ages 16 and 24, impacting growth and metabolic processes.

Cite This Study

Bergström et al. (2026) studied this question.

synapsesocial.com/papers/69eb0ac4553a5433e34b4b84https://doi.org/10.1038/s41467-026-72095-3
View Full Paper
Ask AI
Bookmark
Share