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April 24, 2026RSC AdvancesOpen Access

Preparation of amorphous calcium phosphate nanoparticles using small organic molecules for biomimetic mineralization of dentin

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Authors

ZLZhenni LiuDLDan LiXSXiujun Shi

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Overview

Demonstrates enhanced dentin repair through biomimetic mineralization with ACP-based composites, indicating effective stabilization methods.

Key Points

  • The aim is to prepare nanoparticles of amorphous calcium phosphate for effective dentin repair.
  • Utilized small organic molecules IP6 and H6L for stabilization
  • Measured the effects on phase transformation of ACP
  • Assessed tubule occlusion capabilities of the composites
  • IP6 and H6L successfully inhibited phase transformation of ACP
  • ACP-based composites showed superior tubule occlusion
  • Enhanced biomimetic mineralization was demonstrated for dentin repair

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69eb0bc7553a5433e34b5565https://doi.org/10.1039/d5ra10131j
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Formation of Stable Amorphous Calcium Phosphate and Collagen Assemblies by a Versatile Spray‐Drying Approach2026
  2. 2Dental adhesive loaded with amorphous calcium phosphate for occlusion of dentinal tubules2025
  3. 3Bioinspired Dormant‐ATP‐Stabilized Biomineral Amorphous Nanoparticles and Saliva‐Activated Rapid Mineralization Toward High‐Performance Dental Enamel Restoration2026
  4. 4Bioactive Polymeric Composites for Tooth Mineral Regeneration: Physicochemical and Cellular Aspects2011 · 35 citations
  5. 5Glycine-mediated surface stabilization of amorphous calcium phosphate nanoparticles for biointeractive thin-film formation2026