Inflammatory bowel disease and Primary sclerosing cholangitis: immunological links and clinical outlook

Key Points

• The aim is to explore the immunological connections between inflammatory bowel disease and primary sclerosing cholangitis, highlighting future management approaches.
• Reviewed current management strategies for PSC-IBD overlap syndrome
• Discussed potential novel agents targeting immune and microbial pathways
• Highlighted the importance of multidisciplinary collaboration across specialties
• Current therapies do not stop disease progression
• Novel agents targeting immune and microbial pathways show promise
• Future strategies emphasize precision medicine for better disease management

Abstract