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April 25, 2026Systematic Reviews0 citationsOpen Access

A methodologic survey on use of the GRADE approach in evidence syntheses published in high-impact factor neurology journals

AVAnna Balsamão VazJVJúlia Mafra VasconcelosPCPollyana Helena Vieira Costa

Key Points

  • This study aims to assess the use of the GRADE system in systematic and scoping reviews within top neurology journals.
  • Selected top 13 neurology journals according to Scopus Sources from 2020 to 2022.
  • Included all systematic and scoping reviews that utilized the original GRADE system.
  • Data were extracted and analyzed by three researchers for classification.
  • Only 16.7% of systematic reviews from Neurorehabilitation and Neural Repair used GRADE.
  • 4.8% of the Journal of Stroke and Cerebrovascular Diseases included GRADE in their reviews.
  • Risk of bias and imprecision were the most commonly used downgrading criteria (100%).

Abstract

The GRADE system is a transparent approach to assess the quality of evidence and strength of recommendations in health. It aids in converting evidence into guidelines, enhancing clarity and application in clinical practice. This study aims to identify scoping and systematic reviews using GRADE in top rehabilitation and neurology journals from 2020 to 2022. The top 13 journals of rehabilitation and/or neurology area were selected by Scopus Sources. All systematic reviews and scoping reviews published between 2020 and 2022 were included. Studies that did not use the original GRADE system or failed to describe the GRADE details were excluded. The data of interest were extracted and analyzed by three researchers for an Excel table. There is no relation between the journals’ quality and the number of systematic reviews that used the GRADE system. The Neurorehabilitation and Neural Repair and Journal of Stroke and Cerebrovascular Diseases had the highest number of systematic reviews that used the GRADE system (16.7% and 4.8%, respectively). The most used downgrading criteria are both risk of bias and imprecision (100%). The GRADE system is not widely used in the top 13 journals in the rehabilitation and neurology journals.

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Cite This Study

Vaz et al. (2026) studied this question.

synapsesocial.com/papers/69ec5a8888ba6daa22dac0c9https://doi.org/10.1186/s13643-025-02928-7
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Also Consider

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  1. 1Evaluating Guideline and Registration Policies Among Neurology Journals: A Cross-Sectional Analysis.2024
  2. 2From Significance to Certainty: Using Grading of Recommendations, Assessment, Development, and Evaluation to Translate Evidence into Trustworthy Recommendations2026
  3. 3Exploring the application of GRADE in formulating WHO public health guidelines: a scoping evidence review2026
  4. 4An emerging consensus on grading recommendations?2006 · 142 citations
  5. 5Pediatric dentistry systematic reviews using the GRADE approach: methodological study2024