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April 26, 2026Gut MicrobesOpen Access

Gut microbiome and pregnancy complications: emerging evidence and mechanistic insights

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Authors

SHShijia HuZMZelei MiaoCXCongmei Xiao

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Overview

Review identifies links between gut microbiome changes and pregnancy complications, suggesting implications for maternal health.

Key Points

  • This review aims to synthesize evidence linking changes in the gut microbiome with pregnancy complications and their underlying mechanisms.
  • Reviewed current literature on gut microbiome changes during pregnancy.
  • Examined relationships between microbial communities and pregnancy complications.
  • Summarized mechanisms involving metabolites and maternal immune responses.
  • Altered gut microbiome associated with complications such as miscarriage, gestational diabetes, and preeclampsia.
  • Key metabolites like short-chain fatty acids and bile acids play a role in these complications.
  • Maternal microbiome affects offspring health through vertical transmission and developmental programming.

Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/69edac074a46254e215b3d63https://doi.org/10.1080/19490976.2026.2661417
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