Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 26, 2026Food Chemistry XOpen Access

From fruit to function: Squalene synthase driven triterpenoids biosynthesis in Gardenia jasminoides for food-active ingredient discovery

View Full Paper
Ask AI
Bookmark
Share

Authors

WWWuke WeiYMYilin MaoDCDaxia Chen

Discussion

Loading...

Member takes

Overview

Randomized trial explores triterpenoid production in Gardenia jasminoides, suggesting potential for functional foods.

Key Points

  • The aim is to investigate the biosynthesis of triterpenoids in Gardenia jasminoides and validate the role of squalene synthase (GjSQS).
  • Integrated GC–MS/LC-MS metabolomics assessed triterpenoid accumulation in G. jasminoides fruits.
  • Functional validation confirmed GjSQS expression and localization in the endoplasmic reticulum.
  • A dual-ionization LC-MS approach revealed previously undetectable acidic triterpenoids.
  • Triterpenoids identified include squalene (220 ng/mg FW) and methyl oleanonate (anticancer activity).
  • GjSQS expression strongly correlates with triterpenoid quantity, acting as a rate-limiting factor.
  • The new dual-ionization method identified more tissue-specific acidic triterpenoids than previously detected.

Cite This Study

Wei et al. (2026) studied this question.

synapsesocial.com/papers/69edac074a46254e215b3dd3https://doi.org/10.1016/j.fochx.2026.103871
View Full Paper
Ask AI
Bookmark
Share