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April 26, 2026European Journal of Neurology0 citationsOpen Access

Diffuse Infiltrating Perisellar Mass Mimicking Polyneuritis Cranialis

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PKPaul Philipp KastnerPNPia Lena NiederauGPGeorgios Pantazis

Key Points

  • To describe a rare case of primary bony skull base DLBCL presenting as perisellar infiltration causing complex oculomotor dysfunction.
  • Case report detailing imaging findings and clinical presentation.
  • Use of skull base MRI for diagnosis.
  • Exploration of CSF-based molecular markers for additional diagnostic support.
  • Primary bony skull base DLBCL was confirmed via imaging and molecular analysis.
  • Oculomotor dysfunction linked to perisellar infiltration was highlighted.
  • Skull base MRI proved essential for accurate diagnosis of cranial neuropathy.

Abstract

This case illustrates a rare presentation of primary bony skull base DLBCL with perisellar infiltration, highlighting the diagnostic challenges of complex oculomotor dysfunction. Dedicated skull base MRI is essential in the workup of unexplained cranial neuropathy. CSF-based molecular markers may complement the diagnostic approach in similar presentations.

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Cite This Study

Kastner et al. (2026) studied this question.

synapsesocial.com/papers/69edacbd4a46254e215b4652https://doi.org/10.1111/ene.70600
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