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This review aims to synthesize findings on the cytotoxicity of carbon dots and the factors influencing their biological interactions.

Understanding the Toxicity of Carbon Dots: The Role of Synthesis Variability, Surface Chemistry, and Biological Context

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Review integrates findings on carbon dots cytotoxicity in various biological contexts, suggesting implications for nanomedicine.

This review aims to synthesize findings on the cytotoxicity of carbon dots and the factors influencing their biological interactions.
Review of cytotoxicity studies published over the last decade.
Analysis of synthesis methods including hydrothermal, microwave, and chemical reduction.
Examination of in vivo studies involving animal models like zebrafish, mice, and planarians.
Carbon dots exhibit low toxicity at certain concentrations but can cause oxidative stress and organ damage at high doses.
Positive surface charges lead to higher cellular uptake and increased cytotoxicity compared to negative charges.
The route of administration significantly influences observed toxicity profiles.

Shabbir et al. (2026) studied this question.

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View Full Paper

Ask AI

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Authors

Review integrates findings on carbon dots cytotoxicity in various biological contexts, suggesting implications for nanomedicine.

This review aims to synthesize findings on the cytotoxicity of carbon dots and the factors influencing their biological interactions.
Review of cytotoxicity studies published over the last decade.
Analysis of synthesis methods including hydrothermal, microwave, and chemical reduction.
Examination of in vivo studies involving animal models like zebrafish, mice, and planarians.
Carbon dots exhibit low toxicity at certain concentrations but can cause oxidative stress and organ damage at high doses.
Positive surface charges lead to higher cellular uptake and increased cytotoxicity compared to negative charges.
The route of administration significantly influences observed toxicity profiles.

Shabbir et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark