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April 27, 2026Journal of neurosurgery0 citations

Resection and permanent intracranial brachytherapy using modular, biocompatible cesium-131 implants for recurrent aggressive meningiomas: 5-year results from a prospective phase 2 trial

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KLKatriel E. LeeJCJoshua S. CatapanoJEJennifer M. Eschbacher

Key Points

  • The aim is to evaluate the effectiveness of resection combined with Cs-131 brachytherapy in managing recurrent aggressive meningiomas.
  • Conducted a prospective phase 2 trial
  • Performed resection and permanent intracranial brachytherapy using cesium-131 implants
  • Assessed local control and complication rates over 5 years
  • Significantly improved local control compared to prior treatments at the same site
  • Acceptable rates of complications observed in the patient cohort

Abstract

This study shows that resection combined with Cs-131 CTBT resulted in significantly improved local control with acceptable complications in patients with recurrent aggressive meningiomas when compared with the prior treatment at the same site.

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Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/69eefc6dfede9185760d3820https://doi.org/10.3171/2025.12.jns25868
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