A Case of Anaphylactic Shock Induced by Nafamostat Mesylate During Hemodialysis with Elevated Serum Tryptase Levels

Key Points

• To investigate a case of anaphylactic shock induced by nafamostat mesylate during hemodialysis and examine the diagnostic utility of serum tryptase levels.
• Case report of a 72-year-old male experiencing anaphylactic shock after hemodialysis using nafamostat mesylate.
• Performed prick tests and blood tests to evaluate allergic reactions and measure serum tryptase levels.
• Discontinued nafamostat mesylate during hemodialysis to monitor symptom recurrence.
• The patient exhibited elevated serum tryptase levels during the incident, confirming anaphylactic shock.
• Prick test was positive for nafamostat mesylate, establishing the diagnosis.
• No symptom recurrence was noted after discontinuation of nafamostat mesylate during hemodialysis.